克罗地亚组织的国家结肠直肠癌查计划的成本效益
August Cesarec1, Nataša Antoljak2,3, Ivana Brkić Biloš2
1Faculty of Economics and Business, University of Zagreb, 10000 Zagreb, Croatia.
Cancers
|January 10, 2026
概括
在克罗地亚,便免疫化学检测 (FIT) 对结直肠癌查的成本效益高于瓜亚便隐性血液检测 (gFOBT). FIT改善了健康结果并降低了成本,使其成为国家查计划的首选策略.
科学领域:
- 公共卫生 公共卫生
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
背景情况:
- 结肠直肠癌是克罗地亚癌症诊断和死亡的主要原因.
- 克罗地亚在2007年实施了一项国家查计划,每两年对50-74岁的个人进行瓜亚便隐性血液测试 (gFOBT).
- 目前的查策略需要对成本效益和潜在改进进行评估.
研究的目的:
- 分析克罗地亚结直肠癌的经济负担.
- 为了比较没有查,两年一次的gFOBT和两年一次的便免疫化学测试 (FIT) 的成本效益.
- 确定克罗地亚结直肠癌的最佳查策略.
主要方法:
- 开发了一个模拟模型来比较三个结直肠癌查场景.
- 该模型预测了50岁以上1万名年龄组的5年健康结果和成本.
- 关键结果包括癌症诊断,死亡率,获得的生命年数和获得的生命年成本.
主要成果:
- 晚期结直肠癌的治疗费用 (39802欧元) 显著超过所有阶段的平均费用 (16897欧元).
- 与没有查相比,gFOBT和FIT查策略都显示出改善的健康结果和降低的成本.
- 便免疫化学测试 (FIT) 成为首选的策略,因为其灵敏度更高,健康结果更好,成本低于gFOBT.
结论:
- 在克罗地亚实施FIT查而不是gFOBT可以提高结直肠癌查的普及率.
- 采用FIT预计将改善患者的健康结果,并降低整体医疗保健支出.
- 转向FIT查可以显著减少与结直肠癌相关的经济负担.
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