相关实验视频

Updated: Jan 13, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
08:35

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

6.3K

在人类神经分化过程中特定阶段的替代多化,通过综合长读和短读测序揭示了这一点

Zheqi Lou1, Xianyan Zeng1,2, Tinghui Jiang1

  • 1College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.

Biology
|January 10, 2026
PubMed
概括

这项研究揭示了在人类胚胎干细胞 (hESC) 神经分化过程中对替代多基化 (APA) 的新见解. 这项研究确定了数千个新的转录和多个A位点,增强了我们对细胞法特调节的理解.

关键词:
牛津纳米孔技术公司替代性的多基化.埃克森的替代性多基化.人类胚胎干细胞内部的替代性多基化.神经分化的神经分化.简读序列的短读序列是什么

更多相关视频

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay11:22

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay

Published on: August 26, 2018

9.2K
Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes10:48

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes

Published on: April 12, 2015

10.5K

相关概念视频

Alternative RNA Splicing02:18

Alternative RNA Splicing

Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
24.6K
RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
11.7K