肉类消费与慢性阻塞性肺病风险相关:系统性审查和元分析
Yutong Chen1, Hui Xia1, Bihuan Hu1
1Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China.
Nutrients
|January 10, 2026
概括
肉类消费与慢性阻塞性肺病 (COPD) 的风险增加有关. 虽然鱼类的摄入量显示出一种保护作用,但加工和制的肉类与较高的COPD风险有关,因此需要进一步调查肉类亚型.
科学领域:
- 肺部医学 肺部医学
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 代表了全球重要的健康负担.
- 饮食因素,包括肉类消费,都与COPD风险有关.
- 需要综合证据来澄清肉类摄入量与COPD之间的关联.
研究的目的:
- 进行系统审查和元分析.
- 评估不同类型的肉类消费与COPD风险之间的关联.
- 综合现有的关于这个主题的观察性研究数据.
主要方法:
- 在PubMed和Web of Science的综合文献搜索.
- 在元分析中包含15项观察性研究.
- 使用森林地块,I2统计,子组分析,道地块和埃格尔测试来评估异质性和出版偏差的统计分析.
主要成果:
- 总肉类消费显示,COPD风险增加的几率比 (OR) 为1.15 (95% CI:1.01-1.31).
- 鱼类消费 (OR:0.84;95%CI:0.72-0.97) 是保护性的,而加工肉类 (OR:1.18;95%CI:1.02-1.37) 和肉 (OR:1.64;95%CI:1.41-1.90) 与更高的风险有关.
- 亚组分析表明,在横截面和病例对照研究中,以及在较大的参与者群体中,风险增加.
结论:
- 总体肉类消费与COPD风险之间存在显著的关联.
- 在研究设计,特别是队列研究中,异质性和不一致的发现减弱了证据的强度.
- 建议对标准化分类进行进一步研究,并专注于肉类亚型,以澄清这些关联.
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