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Updated: Jan 13, 2026

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减轻体重增加的副作用 通过减少青少年饮用含糖饮料的消费,减轻体重增加的副作用 新处方的第二代抗精神病药物
Kristin Bussell1,2, Heidi Wehring2, Susan dosReis3
1Department of Family and Community Health, University of Maryland School of Nursing, Baltimore, MD 21201, USA.
Nutrients
|January 10, 2026
概括
这项研究发现,向服用抗精神病药物的年轻人提供免费瓶装水和家庭支持,改善了饮水量,并减少了含糖饮料的消费. 然而,这项干预措施并没有在六个月内显著防止不健康的体重增加.
科学领域:
- 儿科 儿科 儿科
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 年轻人使用抗精神病药物 (APM) 与代谢风险有关,如体重增加和2型糖尿病.
- 第二代APM通常用于治疗青少年的精神疾病.
- 生活方式干预对于减轻儿科患者APM相关健康风险至关重要.
研究的目的:
- 评估健康生活方式干预措施在增加水摄入量和减少含糖饮料 (SSB) 消费方面的有效性.
- 为了防止不健康的体重增加,年轻人开始第二代APM.
- 评估家庭送水和家庭支持对代谢健康指标的影响.
主要方法:
- 一项随机对照试验,涉及148名医疗补助保险青少年 (8-17岁) 开始APM.
- 干预组每两周一次收到家庭送达的瓶装水和家长的电话支持.
- 评估包括基线,3个月和6个月的身高/体重和饮食摄入量;统计分析使用线性混合模型.
主要成果:
- 在3个月或6个月后,BMIz-score中没有观察到显著的群体间差异.
- 与对照组相比,干预组在3个月和6个月后显著增加了饮水量.
- 治疗组从基线到3个月的SSB摄入量初步下降,但在6个月后没有发现SSB摄入量的显著差异.
结论:
- 该干预措施成功地改善了水的消耗,并最初减少了青少年在APM上的SSB摄入量.
- 在研究期间,干预组和对照组都没有经历不健康的BMI z-score增加 (>0.5%).
- 需要进一步的研究来为这个脆弱的人群开发可持续的生活方式干预措施.
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