第一季度维生素D缺乏和孕期糖尿病的风险在墨西哥队列中
Lidia Arce-Sánchez1, Isabel González-Ludlow2, Ileana Lizano-Jubert3,4
1Coordination of Endocrinology, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City 11000, Mexico.
Nutrients
|January 10, 2026
概括
墨西哥妇女在头三个月内缺乏维生素D显著增加患妊娠糖尿病 (GDM) 的风险. 在怀孕期间监测和补充维生素D对于降低GDM风险至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 维生素D缺乏与不良的围产期结局有关.
- 怀孕早期的维生素D状况可能会影响妊娠期糖尿病 (GDM) 的发展.
研究的目的:
- 在墨西哥人口中调查第一季度维生素D缺乏和GDM之间的联系.
- 为了比较有和没有维生素D缺乏的孕妇之间的不良产周结局 (APOs).
主要方法:
- 来自OBESO队列的404名孕妇被评估了维生素D水平 (怀孕11-14周).
- 维生素D缺乏症被定义为<20.0 ng/mL.
- 计算了包括GDM在内的APOs的调整几率比率 (aOR),控制了BMI和肥胖.
主要成果:
- 40.5%的女性表现出维生素D缺乏.
- 维生素D缺乏与更高的GDM风险相关 (aOR2.04;95% CI 1.14-3.65).
- 维生素D缺乏与其他APO之间没有发现显著的关联.
结论:
- 在这个墨西哥队列中,第一季度的维生素D缺乏是普遍存在的 (40.5%).
- 怀孕早期的维生素D缺乏是GDM的一个独立风险因素.
- 在怀孕期间建议对维生素D进行监测和补充,以减轻GDM风险.
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