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在食品和环境样本中分析新兴有机污染物的小型化LC:最近的进展和应用

Cemil Aydoğan^1,2,3, Ashraf Ali⁴, Mehmet Atakay⁵

¹Food Analysis and Research Laboratory, Bingöl University, 12000 Bingöl, Türkiye.

Molecules (Basel, Switzerland)

|January 10, 2026

概括

迷你LC系统提供食品和环境污染物的绿色,敏感的分析. 将微量样本准备与Mini-LC和质谱学相结合,可以提高新出现的有机污染物的检测.

科学领域:

分析化学分析化学
环境科学环境科学
食品安全食品安全

背景情况:

微型液态染色学 (Mini-LC) 系统,包括毛细液态LC (Cap-LC),纳米LC和芯片LC,为传统LC提供可持续的替代方案.
这些系统减少了溶剂的使用,提高了分离效率,并促进了环保的分析操作.
集成微尺度样品制备技术,如微固态相提取 (μ-SPE),管内固态相微提取 (IT-SPME),液态相微提取 (LPME) 和QuEChERS,可以提高Mini-LC的灵敏度和选择性.

研究的目的:

审查Mini-LC应用程序的最新进展,用于分析食品和环境样本中的新兴有机污染物 (EOC).
批判性地评价2022年初至2025年中期出版的作品.
讨论将Mini-LC技术与质谱学 (MS) 结合使用,用于EOC检测.

主要方法:

迷你LC系统 (Cap-LC,Nano-LC,Chip-LC) 与微量样本准备 (μ-SPE,IT-SPME,LPME,QuEChERS) 相结合.
应用Mini-LC与质谱学 (低分辨率MS和高分辨率MS) 相结合.
从2022年初到2025年中期发表的研究文献综述.

主要成果:

迷你LC与MS相结合,在检测农药,制药,兽药残留物,和多基物质 (PFAS) 和真菌毒素的微量水平方面表现出很高的性能.
微样本制备技术的成功整合显著提高了分析灵敏度和选择性.
迷你LC平台显示出对EOCs具有成本效益,高灵敏度,绿色监测的希望.

结论:

迷你LC,特别是当与微样本制备和质谱学集成时,是分析食品和环境矩阵中的EOC的强大工具.
尽管存在诸如矩阵效应和仪器稳定性等挑战,Mini-LC为污染物监测提供了一种可持续和高效的方法.
迷你LC技术的持续进步对于解决现代食品安全和环境分析的复杂性至关重要.

关键词:

毛细血管-LC 的情况.芯片LC-LC是什么意思在Nano-LC中使用Nano-LC.新出现的有机污染物 (EOCs)菌类毒素 (mycotoxins) 是一种有毒的物质.杀虫剂杀虫剂杀虫剂兽医药物兽医药物兽医药物

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