多学科团队与聊天之间的一致性GPT-4o决策:系统性自身免疫性风湿性疾病中的盲目,横截面一致性研究
Firdevs Ulutaş1, Göksel Altınışık2, Gülay Güngör3
1Division of Rheumatology, Department of Internal Medicine, Pamukkale University Faculty of Medicine, 20000 Denizli, Türkiye.
Diagnostics (Basel, Switzerland)
|January 10, 2026
概括
人工智能 (AI) 在诊断和管理系统性自身免疫性类风湿性疾病 (SARDs) 方面与多学科团队 (MDTs) 达成适度一致. 人工智能可以在复杂的病例中协助MDT,改善SARD患者的诊断和治疗决策.
科学领域:
- 医疗信息学 医疗信息学
- 人工智能在医学中的应用
- 类风湿病学 类风湿病学
背景情况:
- 人工智能 (AI) 越来越多地被用于医学诊断.
- 系统性自身免疫性类风湿性疾病 (SARDs) 往往需要多学科团队 (MDT) 的投入来诊断和管理.
- 将AI产生的决策与MDT专家的共识进行比较,对于评估AI的临床实用性至关重要.
研究的目的:
- 将人工智能 (ChatGPT-4o) 的诊断,治疗和监测决策与多学科团队 (MDT) 在SARD患者中的决策进行比较.
- 评估AI和MDT决策在患者护理的各个方面之间的一致性,包括诊断,治疗和随访.
- 评估AI作为管理复杂SARD病例的辅助工具的潜力.
主要方法:
- 一项涉及已成年患者 (≥18岁) 的横截面一致性研究,确认了SARD和最近的MDT决定.
- 人工智能 (ChatGPT-4o) 基于标准化提示生成单次会议决策,对MDT结果视而不见.
- 在六个关键领域进行了决策比较:临床诊断,放射性诊断,抗炎治疗,抗纤维治疗,无药物随访和进一步调查.
- 科恩的Kappa (κ) 统计数据被用来量化AI和MDT决策之间的一致性,并使用R软件 (4.3.2版本) 进行分析.
主要成果:
- 该研究包括47名患者,主要是女性 (61.70%),平均年龄为61.74岁. 风湿性关节炎 (RA) 是最常见的诊断 (31.91%).
- 在所有决策类型中都发现了统计学上显著的一致性.
- 在临床诊断方面观察到中度一致 (κ = 0.52). 对于免疫抑制治疗和无药物随访决策,分别发现了更高的一致性 (κ = 0.64和 κ = 0.67).
- 对放射性诊断 (κ = 0.55),抗纤维素治疗 (κ = 0.49) 和进一步调查 (κ = 0.45) 的同意也处于中度范围.
结论:
- 人工智能在管理肺部参与的SARD时,与MDT决策有适度的一致性.
- 人工智能可以为复杂SARD病例的临床和放射性诊断,治疗选择和后续计划提供宝贵的见解.
- 人工智能显示出作为补充工具的潜力,以支持类风湿病的MDT决策,特别是对于具有挑战性的患者病例.
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