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Updated: May 5, 2026

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对哺乳动物和水生系统中纳米塑料毒性的比较代谢方法

Junhyuk Lee1, Hyeonji Jang2, Boyun Kim1

  • 1College of Fisheries Science, Pukyong National University, Busan 48513, Republic of Korea.

International journal of molecular sciences
|January 10, 2026
PubMed
概括

纳米塑料 (NP) 破坏细胞平衡,导致哺乳动物和水生生物的代谢问题. 代谢学揭示了NP如何影响脂质,TCA循环和氨基酸通路,影响能量和氧化还原平衡.

关键词:
脂质组的类型代谢 代谢 代谢 代谢代谢生物组的代谢生物组纳米塑料是一种纳米塑料.纳米毒性 纳米毒性

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Toxicity Testing in Animals01:23

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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