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自动反应性CD4+CD8+ T细胞杂交瘤从Sjögren病模型的建立,SATB1条件淘汰赛小鼠

Shuhei Mashimo1,2,3, Michitsune Arita1, Taku Kuwabara1

  • 1Department of Molecular Immunology, Toho University School of Medicine, Tokyo 143-8540, Japan.

International journal of molecular sciences
|January 10, 2026
PubMed
概括

斯约格伦病包括眼睛和口腔干燥. 在SATB1cKO小鼠中,唾液腺中的异常CD4+CD8+双阳性T细胞表明在自身免疫病原发生过程中发挥了作用.

关键词:
斯约格伦病是Sjögren的疾病.一个T细胞杂交瘤.T细胞受体受体的 T 细胞受体.这是自身免疫力.确定互补性的地区3

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