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Updated: Jan 13, 2026

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ATAC-Seq和RNA-Seq的整合揭示了黑色素可访问性和转录动态在木的水果颜色发育过程中

Yichun Zeng^1,2, Yilei Wu^1,2, Jie Dai^1,2

¹Sericulture Research Institute, Sichuan Academy of Agricultural Sciences (Institute of Special Economic Animal and Plant, Sichuan Academy of Agricultural Sciences), Nanchong 637000, China.

International journal of molecular sciences

|January 10, 2026

概括

研究人员绘制了木水果发育中的基因调节图,以了解水果的颜色和质量是如何控制的. 这项研究确定了影响糖,黄和酸生物合成的关键因素.

科学领域:

植物生物学植物生物学
基因组学就是基因组学.
生物化学生物化学

背景情况:

桑 (Morus spp.) 的水果颜色. 是一个关键的特征,具有多样化的变化.
控制木果色素和发育的分子机制尚未得到充分理解.

研究的目的:

在木果的发育过程中调查全基因组的染色质可访问性和基因表达.
识别转录因子和控制水果质量特征的监管网络.

主要方法:

ATAC-seq (使用测序测定转化酶可访问染色质的测试) 和RNA-seq (RNA测序) 的整合.
对差异可访问的染色体区域和差异表达的基因的分析.
重建转录性调节网络和图案丰富分析.

主要成果:

生成了调节元件和转录活动的全基因组图.
确定了参与糖类,黄类,二类和氨酸生物合成的候选转录因子和基因.
揭示了在不同发育阶段调节基因表达的关键 cis 元素.

结论:

这项研究提供了一个全面的了解监管架构的管理树果成熟.
已识别的调节网络和候选基因为改善木果质量和产量提供了基础.
生成的数据集有助于进一步研究果发育的非特征性特征.

关键词:

ATAC-seqq 的使用情况.在RNA-seqqq.树的树,就是树的树.转录因子是一种转录因子.

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