被忽视的职业风险因素 - - 导致肺癌诊断延迟的一个因素
Cristina Mandanach1,2, Andreea Maftei1, Ocxana Maria Țocan1
1Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 020021 Bucharest, Romania.
Healthcare (Basel, Switzerland)
|January 10, 2026
概括
职业暴露显著增加了肺癌患者的诊断延迟. 识别和解决职业风险对于早期肺癌诊断和治疗启动至关重要.
科学领域:
- 职业医学 职业医学是专业的.
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
背景情况:
- 及时诊断肺癌对于有效治疗至关重要,指南建议在症状出现后两个月内开始治疗.
- 减少诊断的总间隔时间 (TITD) 是必不可少的,需要初级医生进行适当的风险评估.
研究的目的:
- 评估职业暴露对从症状发作到确诊的肺癌诊断延迟的影响.
主要方法:
- 分析了110名肺癌患者,分为高风险职业暴露和对照组.
- 数据包括职业史,年龄,性别,教育,健康素养,吸烟史,家族史和以前的肺部疾病.
主要成果:
- 34.55%的患者因职业暴露而被归类为高风险患者.
- 高风险组的TITD显着更长 (p=0.03),其中55.17%的患者经历了较长的延迟,而对照组的44.83% (p=0.006).
- 在多变量分析中,职业暴露是较长TITD的唯一显著预测因素 (OR=10.57,p=0.01).
结论:
- 暴露的工人和医疗保健提供者对职业风险的提高意识可以缩短肺癌诊断间隔.
- 识别高职业暴露的个体对于积极的诊断策略至关重要.
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