在不同的临床和微生物学环境中,突周围假肢感染标记物显示出高度的可变性
Joachim Ortmayr1, Jennifer Straub1, Klemens Vertesich1
1Department of Orthopaedics and Trauma Surgery, Division of Orthopaedics, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Journal of clinical medicine
|January 10, 2026
概括
同胞白细胞计数 (WBC) 和多态核细胞百分比 (PMN) 对于诊断周围假肢关节感染 (PJI) 是有价值的. 它们的水平因感染毒性,症状持续时间和病原体检测而有所不同,有助于复杂的PJI诊断.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 医学诊断 医学诊断 医学诊断
背景情况:
- 诊断周围假肢关节感染 (PJI) 是一个挑战,特别是在低度感染.
- 当其他诊断方法无法得出结论时,像白细胞计数 (WBC) 和多态核核百分比 (PMN) 这样的突液标记物至关重要.
研究的目的:
- 评估突白血细胞和PMN在周围假肢关节感染 (PJI) 的诊断效用.
- 评估WBC和PMN水平如何受到感染毒性,组织学,症状持续时间和病原体检测的影响.
主要方法:
- 对115名被诊断患有PJI的患者进行了回顾性分析.
- 在不同的临床和微生物学子组中比较交膜白血球和PMN:低病毒性病原体与高病毒性病原体,阴性与阳性组织学,症状持续时间 (≤4周与>4周) 和病原体检测 (阳性与阴性).
主要成果:
- 在阳性病原体检测和高病毒性病原体的病例中观察到较高的突白血细胞和PMN.
- 升高的WBC和PMN水平与较短的症状持续时间 (≤4周) 相相关.
- 阴性组织学与明显较低的WBC和PMN值有关.
结论:
- 交膜WBC和PMN受病原体毒性,组织学发现,症状发作和成功检测病原体的影响.
- 这些突标记物表现出可变性,突出显示了它们在PJI诊断中的复杂作用.
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