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炎症性肠病中的刺激性肠综合征:基于证据的实用审查
Mohsin F Butt1,2, Mustafa H Reghefaoui3, Aaron Shailesh Benedict2
1NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and The University of Nottingham, Nottingham NG7 2RD, UK.
刺激性肠综合征 (IBS) 症状通常影响静止性炎症性肠病 (IBD) 患者. 生物心理社会方法是管理这些重叠的肠-大脑相互作用障碍的关键.
科学领域:
- 胃肠病学 胃肠病学
- 肠-大脑相互作用
- 炎症性肠道疾病研究研究
背景情况:
- 刺激性肠综合征 (IBS) 是一种肠脑相互作用障碍.
- 大约三分之一的患有静止炎性肠病 (IBD) 的患者会出现IBS类型的症状.
- 这些症状会对生活质量产生负面影响,并使诊断复杂化.
研究的目的:
- 审查静止IBD患者的IBS类型症状的机制,诊断挑战和管理.
- 探索导致这些症状的功能和有机因素之间的相互作用.
- 为解决IBS和IBD之间的重叠提供了一个最新的视角.
主要方法:
- 对当前文学进行叙述性回顾.
- 检查拟议的病理生理机制.
- 对诊断和管理策略的分析.
主要成果:
- 静止性IBD中的IBS症状是由于低级炎症,肠道透性变化,失生症,内脏过敏以及心理社会因素的结合而产生的.
- 诊断需要以症状为重点的方法,不包括活跃的炎症.
- 有效的管理涉及生物心理社会策略,包括饮食,行为疗法和药物.
结论:
- IBS和IBD的共存需要综合管理策略.
- 解决生理和心理方面的问题对于改善患者的治疗结果至关重要.
- 未来的研究应该专注于生物标志物和个性化疗法,以获得更高的精度.
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