手术环境中的药物调和:在多种药物治疗患者中进行的一项横截面研究
Mercedes Jiménez-Heredia1, Vlada Zabrodotska-Maksymyuk2, Carmen Carrión-Carrión3
1Servicio de Farmacia, Hospital Clínic de Barcelona, Calle Villarroel 170, 08036 Barcelona, Spain.
Journal of clinical medicine
|January 10, 2026
概括
多种药物治疗手术患者的药物调整显示出频繁的,临床上显著的差异,突出了改善术后药物管理策略的必要性,以提高患者的安全性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
- 手术护理 手术护理
背景情况:
- 多种药物治疗的手术患者有很高的药物错误风险.
- 术后药物管理是复杂的,容易出现差异.
- 现有的药物调和流程可能无法充分捕捉所有差异.
研究的目的:
- 为了确定药物异常的发生率,性质和临床相关性,在多种药物治疗的手术患者.
- 为了确定与实际药物差异相关的因素.
- 评估这些差异对患者结果的影响.
主要方法:
- 一项涉及预定手术患者服用≥4种慢性药物的横截面研究.
- 使用电子记录和患者访谈进行药物调和.
- 使用SEFH标准将差异分类为合理或真实.
主要成果:
- 86%的分析药物存在差异,其中44%被归类为真实药物.
- 平均每位患者发现了5.7个实际差异.
- 36.8%的实际差异具有潜在的临床严重性,影响心血管和神经系统药物.
结论:
- 在多种药物治疗的手术患者中,常见的和临床相关的药物差异存在.
- 当前的麻醉前报告往往缺乏具体的药物管理建议.
- 需要进一步的研究来制定全面的外科手术期间安全策略.
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