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Updated: Jan 13, 2026

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在非结核菌菌肺部疾病的液和支气管镜样本之间的协同分析
Sojung Park1, Jin Hwa Lee1, Nam Eun Kim1
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul 07985, Republic of Korea.
Journal of clinical medicine
|January 10, 2026
概括
诊断肺非结核菌菌病 (NTM) 显示出唾液和支气管镜样本之间的高度一致性. 大多数患者有匹配的NTM物种,这表明从任何样本类型的可靠诊断.
科学领域:
- 肺部病理学 肺部病理学
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- 非结核菌菌 (NTM) 肺部疾病的诊断依赖于识别致病物种.
- 唾液和支气管镜样本是常见的诊断来源,但它们在NTM识别中的一致性需要评估.
研究的目的:
- 评估和支气管镜样本之间的NTM物种鉴定一致性.
- 根据阳性培养和诊断方法的数量来比较临床结果.
主要方法:
- 从呼吸器样本中分离出NTM的400名患者的回顾性分析 (2010-2022年).
- 评估唾液和支气管镜之间的物种一致性.
- 对影响放射性进展或治疗需要的因素的多变量分析.
主要成果:
- 100名患者接受了支气管镜检查;61名患者在唾液和支气管镜检查之间显示一致的NTM物种.
- 38名患者仅从一个样本类型中分离出NTM;一名患者发现了不一致的物种.
- 较低的BMI,单独隔离组和纤维腔疾病与较差的结果有关.
结论:
- 唾液和支气管镜样本显示了NTM物种识别的高度一致性.
- 大多数NTM肺病的病例可以使用唾液或支气管镜样本可靠地诊断.
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