心脏植入式电子设备相关的传染性内心炎由白菌引起:一个案例报告
Denis Swolana1, Danuta Łoboda2,3, Beata Sarecka-Hujar4
1Department of Microbiology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 4 Jagiellońska Str., 41-200 Sosnowiec, Poland.
Journal of clinical medicine
|January 10, 2026
概括
本案例研究突出了一个罕见的Bacillus cereus感染心脏器械,成功地用奥里塔万和口服万科米治疗. 它强调考虑侵袭性Bacillus cereus感染的胃肠道风险因素.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 微生物学 微生物学
背景情况:
- 全球化和免疫功能低下的患者增加了对机会性病原体的暴露.
- 心脏植入式电子设备相关的传染性内心炎 (CIED-IE) 是一种严重的并发症.
- 谷菌是一种不常见的CIED-IE病因,通常与食物传播疾病有关.
研究的目的:
- 报告来自胃肠道的Bacillus cereus bacteremia引起的CIED-IE病例.
- 讨论CIED患者罕见病原体感染的诊断和治疗挑战.
- 突出特定抗生素治疗方案在治疗这种感染中的作用.
主要方法:
- 一名66岁的女性患者用心脏再同步心脏起器 (CRT-P) 呈现了CIED-IE.
- 进行了透静脉取 (TLE) 和透食管心声谱.
- 术内培养物鉴定出Bacillus cereus;治疗包括oritavancin和口服vancomycin.
主要成果:
- 谷菌被确定为CIED-IE的致病原体.
- 该患者接受了一种非标准的抗生素治疗方案,包括每周服用奥里塔万辛和口服万科米辛.
- 成功的治疗允许重新植入CRT-P,在3个月的随访中没有复发.
结论:
- 侵入性Bacillus cereus感染可能发生,胃肠道因素是潜在的风险因素.
- 扩展的微生物学诊断和定制的抗生素治疗对于罕见或机会性病原体至关重要.
- 奥里塔万辛在治疗CIED-IE这一具有挑战性的病例中表现出有效性.
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