倾斜位置全乳房辐射悖论:我们站在哪里? 一个全面的审查
Chris Monten1, Ilaria Benevento2, Antonietta Montagna2
1Radiation Oncology Unit, Ghent University, B-9000 Ghent, Belgium.
Journal of clinical medicine
|January 10, 2026
概括
俯卧整胸照射 (WBI) 与卧卧治疗相比,提供了剂量测量效益和降低了毒性. 本综述评估了它对大乳房,左侧乳腺癌和节点辐射的优势,以鼓励更广泛的临床采用.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 在过去二十年中,人们对倾斜位置全乳房辐射 (WBI) 的兴趣越来越大.
- 坚实的科学数据显示,易于WBI的剂量测量效益和毒性降低.
- 尽管有证据,但社区对其常规临床采用存在冲突.
研究的目的:
- 评估倾斜位置WBI的现实世界优势.
- 为了将易受WBI影响的特定场景 (如大乳房,左侧乳腺癌和节点辐射) 置于背景.
- 鼓励临床实施易患WBI的方法.
主要方法:
- 在过去的二十年中进行了全面的文献审查.
- 评估针对大/悬浮乳房,左/右乳腺癌和节点辐射的试验.
- 使用光子或质子进行深呼吸呼吸 (DIBH) 的可重现性评估.
主要成果:
- 许多试验已经探索了易受治疗的方法,定义了节点辐射的地图.
- 定制的固定沙发可以促进强度调节辐射疗法 (IMRT) 和体积调节弧线疗法 (VMAT).
- 尽管有越来越多的证据,容易WBI在临床实践中仍未得到充分利用.
结论:
- 普朗WBI具有显著的剂量测量优势和降低毒性.
- 特定场景,如大乳房,左侧乳腺癌和节点辐射受益于易受影响的定位.
- 在日常实践中进一步推广和实施易受WBI的方法是有必要的.
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