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马博克斯感染对孕产妇和胎儿的影响:目前的证据

Stefany Silva Pereira¹, Antonio Braga^2,3,4, Beatriz Bussi Rosolen¹

¹Discipline of Woman Health, Municipal University of São Caetano do Sul (USCS), São Caetano do Sul 09521-160, SP, Brazil.

Journal of clinical medicine

|January 10, 2026

概括

病毒性动物传染性感染Mopox已经在全球范围内传播,呈现出各种症状. 这篇评论详细介绍了它的病毒学,诊断和管理,强调了怀孕中的挑战.

科学领域:

* 病毒学和流行病学
* 公共卫生和传染病

背景情况:

*Mopox是一种新兴的动物性病毒感染,由Orthopoxvirus的Monkeypox病毒引起.
*2022年跨国疫情标志着从本土传播转向持续的人与人传播,主要是通过密切接触.

研究的目的:

* 审查目前关于Mpox病毒学,临床表现,诊断,预防和管理的证据.
*强调产科方面的考虑和公共卫生方面的影响,特别是在怀孕方面.

主要方法:

* 关于Mpox研究的综合文献综述.
*综合有关病毒基因组,临床表现,诊断技术 (PCR,基因组测序) 和治疗选择 (抗病毒药物,疫苗) 的数据.

主要成果:

*Mpox呈现出发烧,淋巴腺病变和粘膜皮肤病变,严重程度因病毒类和宿主因素而异.
*Clade IIb (2022年爆发) 通常会比Clade I引起较轻的疾病,但在脆弱人群中可能会出现严重的结果.
* Tecovirimat是严重病例/高风险群体的潜在抗病毒药物,在怀孕期间安全性数据有限但有利.

结论:

*Mpox管理在很大程度上是支持性的,抗病毒药物和疫苗接种是关键干预措施.
* 由于潜在的垂直传播和不良的围产期结果,怀孕带来了独特的挑战.
*针对性的疫苗接种和对抗病毒安全性的仔细考虑对于管理Mpox至关重要,特别是在孕妇中.

关键词:

诊断诊断诊断诊断诊断诊断母胎结局的结果.的水病毒病毒.一个MPOX的MPOX.传输传输传输传输传输传输疫苗疫苗疫苗疫苗

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