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美国成年人代谢综合征和膀过活之间的关联:NHANES 2005-2018的一项横截面研究
Nianben Chen1,2, Ruiyang Hu3, Jingxing Wu1
1Urology Department, Chuzhou Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Anhui University of Chinese Medicine, Chuzhou, Anhui Province, China.
Medicine
|January 10, 2026
概括
代谢综合征 (MetS) 与过度活性膀 (OAB) 的风险增加有关. 这种关联是非线性的,中度的MetS具有最高的风险,在女性中似乎更强.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 过度活跃的膀 (OAB) 显著影响生活质量.
- 代谢综合征 (MetS) 是一组增加心血管风险的疾病.
- 梅斯和OAB之间的关系需要进一步调查.
研究的目的:
- 调查代谢综合征 (MetS) 和过度活跃的膀 (OAB) 之间的关联.
- 探索剂量-反应关系和这种关联中的潜在改变因素.
主要方法:
- 来自国家健康和营养检查调查 (NHANES) (2005-2018) 的大量队列 (11,078 名参与者) 的分析.
- 应用受限立方线分析和加权多变量逻辑回归.
- 包括基于MetS严重程度,性别,年龄和种族的子组分析.
主要成果:
- 代谢综合征 (MetS) 与过度活跃膀 (OAB) (OR=1.30) 的几率增加显著相关.
- 中度的MetS显示与OAB有显著的关联 (OR=1.61),而严重的MetS没有达到统计学意义.
- 观察到一个显著的非线性剂量反应关系 (P<0.001),风险在更高的MetS严重程度下停滞.
- 在女性中,人们注意到一种更强烈的关联趋势.
结论:
- 代谢综合征 (MetS) 与非线性膀过活 (OAB) 的风险增加有关.
- 这种联系最明显的是中度的MetS严重程度.
- 需要进一步的研究来证实这些发现,并探索潜在的机制.
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