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针对自身免疫性疾病的JAK-STAT信号:目前的理解,临床进展和新兴方向

Zhimin Wu1, Gaojian Lian2, Lvheng He1

  • 1Department of Biochemistry and Molecular Biology, Basic Medical College, University of South China, Hengyang, Hunan, China.

Immunology and cell biology
|January 10, 2026
PubMed
概括

简氏激酶 (JAK) 信号传感器和转录激活器 (STAT) 途径在免疫细胞功能和自身免疫性疾病中至关重要. 抑制剂显示有前途,但需要进一步评估自身免疫性疾病治疗的安全性.

关键词:
自身免疫性疾病是一种自身免疫性疾病.雅克斯坦特信号通道的信号通道.免疫细胞 免疫细胞抑制剂 抑制剂 抑制剂

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