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持续的脑震荡后症状对神经认知,运动和神经生理学的结果的影响

Alexandra N Pauhl¹, Alicia M Kells¹, Christine L W MacNeill²

¹Faculty of Health Sciences, School of Kinesiology, University of Western Ontario, London, Ontario, Canada.

|January 10, 2026

概括

持续的脑震荡后症状 (PPCS) 显著影响神经认知和运动功能. 患有PPCS的女性表现出最严重的平衡和步行缺陷,突出性别特定的恢复模式.

科学领域:

神经科学是一个神经科学.
运动医学运动医学
康复康复康复康复

背景情况:

持续的脑震荡后症状 (PPCS) 是轻度创伤性脑损伤后的一个复杂的挑战.
了解PPCS对各种功能领域的长期影响对于有效的管理和康复至关重要.

研究的目的:

与健康对照组相比,研究PPCS对神经认知,运动和神经生理学的后果.
检查患有PPCS的个体之间的潜在的性别相关结果差异.

主要方法:

一项横截面的研究设计,涉及15名PPCS患者和15名年龄和性别匹配的健康对照.
评估症状报告,神经认知状态,静态和动态平衡,步态和神经生理学 (皮质脊髓刺激/抑制) 使用跨磁刺激.

主要成果:

在PPCS组报告显著更高的症状负担和严重程度.
在PPCS组中观察到整体神经认知表现更差,特别是在注意力方面,女性表现比男性差.
患有PPCS的个体表现出走路性能受损,这一组中的女性表现出最显著的缺陷. 在PPCS组中发现了较大皮质脊髓抑制的趋势,但没有达到统计学意义.

结论:

PPCS与症状报告增加,神经认知和运动功能减弱以及神经生理学变化有关.
患有PPCS的女性特别表现出较差的平衡和步行表现,这强调了需要针对性别的干预措施的需要.

关键词:

脑震荡是一种脑震荡.发动机发动机发动机神经认知神经认知神经生理学神经生理学持续的症状持续的症状

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