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Updated: Aug 2, 2026

Improved Visualization of Lung Metastases at Single Cell Resolution in Mice by Combined In-situ Perfusion of Lung Tissue and X-Gal Staining of lacZ-Tagged Tumor Cells
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在基因工程小鼠模型中,从肺腺癌组织中提取和分类GFP标记核的协议

Katherine Gillis1, Walter A Orellana1, Eric L Snyder2

  • 1Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA; Department of Oncological Sciences, University of Utah, Salt Lake City, UT, USA.

STAR protocols
|January 10, 2026
PubMed
概括

这项研究详细介绍了将GFP阳性核从小鼠肺瘤中分离出来的协议. 这种方法支持高级分析,如染色体免疫沉测序 (ChIP-seq) 和全基因组甲基化研究.

关键词:
癌症 癌症 癌症 癌症在 ChIPIP 中,你会发现.在 ChIPseqq 中使用.染色体免疫沉降的作用流动细胞计量 (Flow Cytometry) 是一种流动细胞计.基因表达 基因表达模型生物模型生物

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...