一种Bifidobacterium衍生的细胞外多糖的体外消化稳定性及其在肠道微生物群调节中的益生菌潜力
Shuyuan Shi1, Yu Wang1, Zixin Han2
1Key Laboratory of Functional Dairy, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Food chemistry
|January 10, 2026
概括
来自Bifidobacterium animalis RH的细胞外多糖 (EPS) 抵抗消化,并充当益生菌. 它们促进有益的肠道细菌,并产生短链脂肪酸,支持肠道健康.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 胃肠病学 胃肠病学
背景情况:
- 细胞外多糖 (EPS) 是重要的微生物代谢物,具有潜在的健康益处.
- 了解特定EPS的消化稳定性和益生菌作用对于功能性食品的开发至关重要.
研究的目的:
- 为了评估Bifidobacterium animalis RH衍生的EPS的消化稳定性.
- 使用体外发酵模型评估这些EPS的益生菌潜力.
- 描述EPS对肠道微生物群组成和功能的影响.
主要方法:
- 在体外消化模型 (INFOGEST 2.0) 评估结构完整性.
- 使用SEM,GPC,IC和FT-IR进行结构性表征.
- 人类便微生物群发酵以分析微生物转移和短链脂肪酸 (SCFA) 生产.
主要成果:
- EPS表现出显著的消化稳定性,保持碳水化合物含量和结构完整性.
- 结构分析证实了保存的分子量和单糖组成.
- 发酵选择性地丰富了有益的肠道细菌 (例如,Bacteroides,Faecalibacterium) 和抑制了病原体,导致pH值降低和SCFA产量增加,特别是丁酸盐.
结论:
- B. animalis RH EPS 具有显著的消化抵抗力和强大的益生菌性质.
- EPS选择性调节肠道微生物群组成,有利于有益细菌和SCFA生产.
- 这些EPS代表了一种有希望的向肠道的功能成分,用于增强肠道健康.
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