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Updated: Jan 13, 2026

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
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One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode

Published on: June 18, 2016

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揭示潜在的Helicobacter pylori疫苗候选者:一个全面的多表位组方法

Amabrilha Virgínia Souza Guimarães1, Alberto Monteiro Dos Santos2, Jéssica de Oliveira Araújo3

  • 1Biosystems and Genomics Informatics Group, René Rachou Institute/Oswaldo Cruz Foundation, 1715 Augusto de Lima Ave, Barro Preto, Belo Horizonte, 30190-002, Minas Gerais, Brazil.

Computers in biology and medicine
|January 10, 2026
PubMed
概括

计算方法确定了针对Helicobacter pylori的潜在疫苗点. 研究人员确切地确定了包括HPpep500在内的特定表位,这些表现出了开发新型H. pylori疫苗以对抗胃肠道疾病的希望.

关键词:
计算表位预测预测计算表位预测计算建模计算建模皮托普与MHC结合的亲和力在Helicobacter Pylori的研究中,分子动力学模拟的模拟.蛋白质数据库中的蛋白质数据库疫苗的目标识别.

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