城市息地类型通过抗生素耐药性基因和金属化物相互作用调节土壤污染和细菌功能特征
Min Wang1, Abolfazl Masoudi2, Can Wang3
1Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, Hebei Collaborative Innovation Center for Eco-Environment, Hebei Research Center of the Basic Discipline of Cellular Biology, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, China; College of Life Sciences, Jishou University, Jishou 416000, China.
Journal of hazardous materials
|January 10, 2026
概括
城市土壤含有抗生素耐药性基因 (ARG) 和金属化物,风险因息地类型而异. 农田和果园显示高ARG风险,而原始植物和残留物污染程度较低,影响生态系统功能和公共健康.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 土壤科学 土壤科学
背景情况:
- 城市土壤是金属化物和抗生素耐药性基因 (ARG) 等污染物的关键储存库.
- 了解多样化的城市息地中的污染物分布对于评估生态系统和公共卫生风险至关重要.
- 息地类型显著影响城市环境中ARG和金属体的同时发生和传播.
研究的目的:
- 在六种不同的城市息地类型中调查ARG,金属化物和细菌功能特征的共同分布.
- 确定息地特定的污染模式和移动遗传元素 (MGE) 动态的驱动因素.
- 评估ARG配置文件,细菌功能和潜在的土壤至人传播途径之间的联系.
主要方法:
- 集成的猎枪元基因组学,16S rRNA测序和定量PCR.
- 采用多变量建模来分析污染物共分布和MGE动态.
- 将ARG的丰度,金属 (?? 化物) 度和与等离子体相关的ARG在植林区,农田,果园,公园,原始植物和半自然残留物中进行比较.
主要成果:
- 农田和果园表现出最高的ARG风险,MGE和生物制剂/金属耐药性基因 (BMRGs) 强烈的共同选择信号.
- 粗土和残留土壤的ARG丰度和金属化物水平显著降低,水平基因转移潜力降低.
- 功能性基因和BMRG是MGE动态的关键驱动因素,而MGE对ARG的直接影响有限;ARG概况与细菌基本功能的中断相关.
结论:
- 息地类型决定了城市土壤中的污染物概况和耐药性基因动员,影响了生态系统服务.
- 抗生素耐药性在城市土壤中的传播是复杂的,受功能基因和BMRGs的影响,而不是仅仅MGE移动性的影响.
- 果园土壤和水果中重叠的ARG突出显示了土壤对人类的潜在传播途径,强调需要综合城市土壤管理战略.
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