对于外围定量计算机断层扫描的参考数据,用于评估印度儿童和青少年的骨质几何和强度
Anuradha Khadilkar1, Chirantap Oza2, Neha Kajale1
1Department of Paediatric growth and Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India; Interdisciplinary School of Health Sciences, Savitribai Phule University, Pune, India.
概括
这项研究为印度儿童使用外围定量计算断层扫描 (pQCT) 提供了关键的骨质几何和强度数据. 这些发现建立了针对年龄和性别的参考曲线,这对于评估儿科骨健康至关重要.
科学领域:
- 儿童骨健康 儿童骨健康
- 骨的发育 骨的发育
- 医疗成像医学成像
背景情况:
- 关于印度儿童的骨质几何和强度的数据有限.
- 现有的参考数据是基于西方人口,可能不适用于印度儿童,因为身高和身体组成的差异.
- 双能X射线吸收度是尺寸依赖的,需要替代方法进行准确的评估.
研究的目的:
- 为印度儿童和青少年的外围定量计算断层扫描 (pQCT) 参数生成特定年龄和性别的参考百分点曲线.
- 为了解决印度儿科人口骨质几何和强度数据的短缺问题.
- 为评估印度儿科骨健康提供一个宝贵的资源.
主要方法:
- 一项横截面的观察性研究,涉及961名健康的印度儿童 (501名男孩),年龄为8-18岁.
- 使用XCT-2000 pQCT扫描仪测量左半径骨参数 (4%和66%的位置).
- 测量参数包括体积椎和皮质密度,极性应力-应变指数,皮质厚度和肌肉面积.
主要成果:
- 呈现的百分位曲线是按年龄,皮层面积和厚度按高度的总密度,状体密度和皮层密度.
- 在17岁 (男孩) 和15岁 (女孩) 时观察到总体体积密度的最大增加.
- 皮层密度在13岁起的女孩中更高;皮层厚度随着年龄的增长显示出性别特异的变化,并且两者都随着身高而急剧增加.
结论:
- 建立了印度儿童和青少年pQCT参数的参考曲线.
- 这些曲线有助于评估儿科骨质几何.
- 为了解印度儿科人口骨发育提供了必要的数据.
相关概念视频
01:55Bone Structure
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
01:18Classification of Bones
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The long...
01:27Compact Bone
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...