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Updated: Jan 13, 2026

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Published on: May 14, 2013

在TROPonin In CArotid Revascularization (TROPICAR) 研究中对TROPonin进行了一年的随访

Ksenija Jovanovic¹, Magnus Jonsson², Joy Roy²

¹Center for Anesthesiology and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

|January 10, 2026

概括

术后心肌损伤 (MI) 经过动脉复血管化后独立预测1年心肌梗塞 (MI). 经历心脏病发作后手术的患者是高风险群体,需要有针对性的策略来减少心脏不良事件.

科学领域:

心血管外科心血管外科
干预心脏病学干预心脏病学
血管医学血管医学

背景情况:

动脉复血管化手术,包括动脉内关节切除术 (CEA) 和动脉支架 (CAS),携带外科手术期间心肌损伤 (MI) 的风险.
了解手术前心肌损伤 (MI) 对心血管再血管化后心血管结果的长期影响,对于患者管理至关重要.

研究的目的:

调查手术前心肌损伤 (MI) 与心血管不良事件 (包括死亡) 之间的关联,在 carotid revascularization 一年后.
在CEA或CAS后一年内识别心肌梗塞 (MI) 的预测因子.

主要方法:

一项前性多中心队列研究招募了527名接受选择性CEA或CAS的患者.
在手术前和手术后测量了高灵敏度心脏类素水平.
患者被跟踪了一年,终点包括心肌梗塞 (MI),中风和死亡率,并使用生存分析进行分析.

主要成果:

95.8%的患者 (n=505) 完成了一年的随访.
心肌梗塞 (MI) 的发生率为2.6%,手术后一年中风为3.8%.
手术后心肌损伤 (MI) 和手术前恶性瘤独立预测了1年的MI (分别为OR=6.54,p=.003和OR=6.13,p=.006). 在手术后心脏病发作的患者中,无心脏病发作的存活率明显较低 (91.9% vs 98.2%,p=.003).

结论:

手术后心肌损伤 (MI) 是 carotid revascularization (CEA或CAS) 后一年内心肌损伤的独立预测因素.
手术后心脏病发作的患者是高风险的子组.
建议针对这一高危人群采取有针对性的策略,以减轻随后的心脏不良事件.

关键词:

冠状动脉狭窄症冠状动脉狭窄后续行动后续行动高灵敏度的心脏托罗邦尼死亡率死亡率死亡率心肌梗塞的心脏病发作在外科手术期间的心肌损伤.

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