从童年到成年时代的重复的时空大脑传播的发育变化
Kyoungseob Byeon1, Hyunjin Park2,3, Shinwon Park1
1Child Mind Institute, New York, NY, USA.
Nature communications
|January 10, 2026
概括
大脑活动模式从童年到成年期成熟,感官关联和任务积极/默认网络传播变得更长. 大脑动态中的这些发育变化支持认知发展.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 大脑发育涉及从童年到青春期的复杂结构和功能变化.
- 神经发育表现出分层模式,在不同大脑区域的成熟度不同.
- 人们对内在大脑活动传播模式的成熟程度还不太了解.
研究的目的:
- 为了研究内在的时空大脑活动传播的发展轨迹.
- 描述这些动态传播如何从童年到成年早期发生变化.
- 探索发育大脑动态和认知功能之间的关系.
主要方法:
- 利用一种新的方法来捕捉大脑活动中的时间延迟动态传播.
- 分析了沿着感官关联 (S-A),任务积极/默认 (TP-D) 和体运动视觉 (SM-V) 轴的内在动态传播.
- 在两个独立队列 (HCP-D和NKI-RS) 中验证的结果.
主要成果:
- 大脑动态从童年到早期成年期向成年人的模式发展.
- 随着成熟,观察到长期发生的SA和TPD传播状态.
- 在发育过程中,SM-V传播状态的流行率下降.
- 上向下S-A传播随着年龄的增长而增加,并且预测认知得分比下向上S-A传播更好.
结论:
- 时空大脑活动传播经历了显著的发育变化.
- 成熟涉及特定传播状态的流行率和持续时间的变化.
- 大脑动态的发育变化,特别是自上而下的SA传播,与认知发展有关.
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