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Updated: Jan 13, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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改造的纤维细胞生长因子1变体,从代性活动中脱离降糖效应,具有治疗2型糖尿病的治疗潜力

Aleksandra A Czyrek1,2,3,4, Daniel Krowarsch1, Szymon Sidor1

  • 1Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, Wroclaw, 50-383, Poland.

Molecular biomedicine
|January 10, 2026
PubMed
概括

工程纤维细胞生长因子1 (FGF1) 变种有效降低血糖,用于2型糖尿病治疗. 这些修改后的FGF1蛋白降低了不必要的细胞增殖,同时保持了强大的降糖效应.

关键词:
纤维细胞生长因子1葡萄糖的吸收量 葡萄糖的吸收降血糖的特性 降血糖的特性减少了繁殖活动.热力学稳定性 热力学稳定性2 型糖尿病 2 型糖尿病

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