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Updated: Jan 13, 2026

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
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GLP-1激动剂通过抑制肺高血压中GSK3β-Drp1信号传递来减少右心室线粒体功能障碍

Lin Zhao1, Yanghong Liu2, Ziwei Ou1

  • 1Department of Cardiovascular Medicine, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.

European journal of medical research
|January 10, 2026
PubMed
概括

作为GLP-1激动剂的塞马格卢提德,在肺高血压 (PH) 模型中有效治疗右心室 (RV) 功能障碍. 它通过准线粒体动态和GSK3β-Drp1信号来改善RV功能.

关键词:
它是一种GLP-1激动剂.线粒体功能 线粒体功能肺动脉高血压 (PAH) 是一种肺动脉高血压.右心室 (RV) 功能障碍/超负荷

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