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Updated: Jul 25, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

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通过使用高度血清性癌症球体和有机物来评估碳烯和PARP抑制剂组合疗效

Emily J Tomas1,2, Jennifer Davis1, Yudith Ramos Valdes1

  • 1Cancer Research Laboratory Program, the Mary and John Knight Translational Ovarian Cancer Research Unit, Verspeeten Family Cancer Centre, London, Canada.

Cancer biology & therapy
|January 11, 2026
PubMed
概括

多 (ADP-ribose) 聚合酶抑制剂 (PARPis) 通过向DNA修复缺陷,在治疗高度血清癌 (HGSC) 方面表现有前途. 虽然一线卡博普拉丁仍然是最佳的,但PARPis在精选的HGSC病例中在化疗前使用时可能会带来好处.

关键词:
在 PARP 抑制剂.上皮卵巢癌 卵巢癌 卵巢癌高等级的血清性癌瘤.有机生物有机物球形状的球形体是指球形状的球体.

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