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Updated: May 6, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device
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MBRA 3.0:整合粘液环境,用于先进的高通量体外微生物组建模型 体外微生物组建模型

Maeva Duquesnoy1, Benoit Chassaing1

  • 1Microbiome-Host Interactions, Institut Pasteur, Université Paris Cité, INSERM U1306, Paris, France.

Gut microbes
|January 11, 2026
PubMed
概括

新的MBRA 3.0系统模拟了肠道的粘液层,揭示了它如何塑造微生物群落及其功能. 这种先进的模型更好地反映了肠道生态,有助于研究胃肠道健康和疾病.

关键词:
在 MBRA 3.0 版本中,MBRA 3.0 是一个非常简单的工具.微生物群中的微生物群在体外模型模型中的体外模型.微生物群的细分化 微生物群的细分化这是粘液粘液.

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相关概念视频

Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
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