相关实验视频
Updated: Jan 13, 2026

08:28
Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
11.2K
多用途和氧化性隐形眼镜消毒溶液的抗菌疗效:系统性审查
Víctor Ponce-García1, Marta-C García-Romera2, María-Carmen Silva-Viguera2
1Department of Optics and Optometry, Universitat Politècnica de Catalunya, Terrassa, Barcelona, Spain.
概括
与多用途溶液 (MPS) 相比,氧化消毒系统对隐形眼镜的抗菌疗效更高. 这尤其适用于对抗性微生物和在具有挑战性的条件下,突出显示了当前ISO测试标准的局限性.
科学领域:
- 眼科和视觉科学 眼科和视觉科学
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
背景情况:
- 隐形眼镜消毒对于预防微生物角膜炎至关重要.
- 多用途溶液 (MPS) 和氧化系统是常见的消毒方法.
- 评估这些系统的实际有效性对于隐形眼镜佩戴者的安全至关重要.
研究的目的:
- 系统地审查和比较多用途溶液 (MPS) 和接触镜片氧化消毒系统 (过氧化和波维-) 的抗菌疗效.
主要方法:
- 使用PubMed和Scopus数据库进行了系统的文献搜索,遵循PRISMA指南.
- 包括的研究将商业隐形眼镜消毒系统与标准参考菌株和临床隔离物进行了比较.
- 数据提取的重点是消毒剂,微生物,ISO合规性,测试方法和结果.
主要成果:
- 氧化系统 (过氧化,波维-) 显示出强大的抗菌活性,通常对有机土壤,生物膜和临床隔离物有效.
- 多用途溶液表现出可变的有效性,其中一些显示对真菌和Acanthamoeba囊的有效性降低.
- 虽然大多数解决方案符合ISO 14729标准,但在几项研究中,在临床相关条件下,疗效显著降低.
结论:
- 氧化系统比MPS提供了优越的抗微生物性能,特别是在具有挑战性的微生物和不利条件下.
- 当前的ISO 14729标准可能会高估消毒剂的使用有效性,因为它们不能完全考虑像Acanthamoeba或耐药菌株等病原体.
- 为了更准确地评估消毒剂的有效性和改善隐形眼镜安全性,需要采用更广泛的微生物的增强测试协议.
相关概念视频
Antimicrobial Effectiveness
894
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
894
Hand hygiene
5.5K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
5.5K
Chemical Agents for Microbial Control
739
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
739
Cleaning, Sterilization, and Disinfection
9.6K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
9.6K
Combined Effects of Drugs: Synergism
6.7K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
6.7K

