在患有杜氏肌肉发育不良症的儿童中参与的环境决定因素
Duygu Mine Alataş1, Mustafa Cemali2, Çiğdem Öksüz3
1Research Assistant, Faculty of Health Sciences, Department of Occupational Therapy, Lokman Hekim University, Ankara, Türkiye.
Pediatric neurology
|January 11, 2026
概括
患有杜恩肌肉发育不良症 (DMD) 的儿童的参与率低于通常发育的同龄人. 环境因素,特别是物理环境,对患有DMD的儿童的参与水平产生重大影响.
科学领域:
- 儿科康复儿童康复中心
- 神经肌肉疾病 神经肌肉疾病
- 儿童发展 儿童发展
背景情况:
- 有限的研究存在于杜申肌力发育不良 (DMD) 的儿童的参与.
- 了解影响参与的因素对于干预计划至关重要.
研究的目的:
- 将患有DMD的儿童与典型发育 (TD) 的男性同龄人之间的参与水平进行比较.
- 研究参与与环境因素之间的关系.
- 评估环境在参与中的作用.
主要方法:
- 横截面研究涉及30名患有DMD的儿童和30名TD的男性儿童 (5-13岁).
- 使用生活习惯评估评估的参与率.
- 用欧洲儿童环境问卷评估的环境条件.
主要成果:
- 患有DMD的儿童的参与得分明显低于TD儿童 (P < 0.001).
- 在总参与率和环境因素之间发现了显著的负相关性 (r = -0.526,P = 0.003).
- 环境因素解释了34.1%的参与差异,物理环境是关键预测因素 (β = -0.517,P = 0.041).
结论:
- 职业治疗师应该系统地评估DMD儿童的参与和环境因素.
- 干预措施应考虑环境修改,以加强参与.
- 物理环境是影响DMD儿童参与的关键因素.
相关概念视频
Satellite Stem Cells and Muscular Dystrophy
2.3K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.3K
Gene-Environment Interactions
1.1K
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
1.1K
Disorders of the Skeletal Muscle
1.7K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
1.7K
Autism Spectrum Disorder
946
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
946
Factors Affecting Pulmonary Ventilation
2.8K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.8K
Sex-linked Disorders
108.2K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
108.2K


