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在使用TIVA进行脊椎手术后,术后尿的性别差异和风险因素
Ansun Jeong1,2, Mira Han3, Noah Hong1
1Department of Neurosurgery, SNU Boramae Hospital, Seoul, Korea.
Journal of Korean Neurosurgical Society
|January 11, 2026
概括
经过全静脉麻醉 (TIVA) 的脊椎手术的男性患者面临更高的术后尿路保留 (POUR) 风险. 关键的危险因素包括骨髓病变,良性前列腺增生 (BPH) 和长时间的麻醉时间.
科学领域:
- 麻醉学 麻醉学
- 神经外科 神经外科
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 手术后尿 (POUR) 是手术后的一个常见并发症.
- 确定POUR的性别特异性风险因素对于有针对性的预防策略至关重要.
- 全静脉麻醉 (TIVA) 经常用于脊椎手术,需要了解其对POUR的影响.
研究的目的:
- 为了确定经过TIVA的脊椎手术的患者中POUR的性别特异性风险因素.
- 为了比较男性和女性患者之间POUR的发病率和风险因素.
主要方法:
- 对446名成年患者 (268名男性,178名女性) 进行了回顾性图表审查,这些患者接受了TIVA的脊椎手术.
- 倾向性得分匹配被用来创建一个由328名患者组成的队列 (164名男性,164名女性).
- 多变量逻辑回归分析确定了POUR的独立风险因素,定义为余尿量≥300mL.
主要成果:
- 与女性相比,男性患者的POUR发病率较高.
- 在男性中,POUR的显著风险因素包括骨髓病变 (aOR,5.17),良性前列腺增生 (BPH) (aOR,2.63) 和延长麻醉时间≥240分钟 (aOR,2.54).
- 骨髓病变和长时间麻醉与整体人口中POUR风险增加有关;女性没有发现任何显著的风险因素.
结论:
- 男性性别,肌肉病,BPH和长时间的麻醉时间是TIVA脊椎手术后POUR的重要风险因素.
- 患有骨髓病变,BPH病史或长期麻醉的男性患者需要对POUR保持高度警.
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