哪一个更能预测死亡率-疼痛严重程度或疼痛干扰? 来自20年纵向数据的证据
Hangqing Ruan1, Yulin Yang2, Hanna Grol-Prokopczyk1
1University at Buffalo, State University of New York, Department of Sociology and Criminology, Buffalo, NY, 14260, USA.
The journal of pain
|January 11, 2026
概括
在老年人中,疼痛干扰或由于疼痛而导致日常活动的限制是死亡风险的更强的预测因素,而不是疼痛严重程度. 解决疼痛的功能影响可能会改善寿命.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 慢性疼痛显著影响生活质量和医疗保健成本.
- 现有的关于疼痛和死亡率的研究不一致,仅限于疼痛干扰.
- 疼痛与死亡率的关系中的社会人口统计学变化还未得到充分研究.
研究的目的:
- 确定疼痛严重程度或疼痛干扰是否是51岁以上美国成年人全因死亡率的更强有力的预测因素.
- 调查这些关联是否因种族/种族,社会经济地位和性别而有所不同.
主要方法:
- 从健康和退休研究中对20年 (1998-2018) 的数据进行了纵向分析 (N=19,487).
- 考克斯的比例危险模型被用来估计死亡风险.
- 乘法相互作用术语评估了社会人口统计学异质性.
主要成果:
- 在调整后的模型中,疼痛的严重程度与死亡风险没有显著关联.
- 疼痛干扰与增加的死亡风险显著相关 (HR: 1.33; 95% CI: 1.27-1.39).
- 疼痛干扰和死亡率之间的关联在种族/种族,性别,教育和财富方面显示出最小的差异.
结论:
- 在老年人中,疼痛干扰是比疼痛严重程度更有力的死亡预测因素.
- 临床医生应评估和解决疼痛干扰,以确定死亡风险.
- 针对疼痛导致的功能限制的干预措施可能会提高寿命.
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