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预测胸内血管大动脉修复干预:使用数字双胞胎技术的概念证明

Anna Ramella¹, Giulia De Campo², Sara Barati¹

¹Department of Chemistry, Materials and Chemical Engineering "G. Natta", Politecnico di Milano, Milan, Italy; AllStent s.r.l., Milan, Italy.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

|January 11, 2026

概括

一个经过验证的数字双胞胎可以准确地预测胸内血管大动脉修复 (TEVAR) 中的支架移植位置. 这项技术增强了手术前规划,旨在减少并发症并改善TEVAR手术中的患者结果.

科学领域:

生物医学工程生物医学工程
医疗成像医学成像
计算力学计算力学计算力学

背景情况:

目前的胸内血管大动脉修复 (TEVAR) 计划依赖于几何评估,忽视了关键的器件-大动脉相互作用.
一个经过验证的高保真性有限元素方法可以复制TEVAR程序.
建立TEVAR数字双胞胎的可信度对于临床整合至关重要.

研究的目的:

为了确定TEVAR数字双胞胎在临床使用中的可信度.
为患者特定的手术前规划提供可靠的工具.
为了验证复制TEVAR的有限元方法.

主要方法:

术前和术后CT血管造影 (CTA) 数据的回顾性分析,来自接受TEVAR的20名患者.
使用水平设置技术对患者特异性解剖学的细分.
创造一个数字双胞胎的勇敢的Captivia支架移植和患者的解剖学.
显式有限元模拟来复制支架移植植入.
使用支架环开口面积百分比错误 (eOA%) 对术后图像重建的模拟准确性的验证.

主要成果:

模拟准确地复制了患者特定解剖学中的支架移植植入.
平均EOA%为4%,始终低于每种支架环的10%.
在近端和远端支架环中观察到较低的误差 (平均<3.7%),这对于密封至关重要.
每个病例的分析大约需要10小时才能完成,比现有文献更准确.

结论:

TEVAR数字双胞胎是可信和验证的,用于预测短期的术后支架移植形状.
数字模拟为患者特定的TEVAR规划提供了一种可靠的方法.
数字双胞胎可以优化程序策略,减少并发症,并改善TEVAR结果.

关键词:

数字双胞胎数字双胞胎数字双胞胎一个有限的元素.数字的数字化支架移植支架移植德瓦尔 (TEVAR) 是一个验证验证验证验证

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