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入院系统性炎症预测肺结核的老年人的吞能力下降
Masayoshi Kakiuchi1, Tatsuro Inoue2, Hikaru Kobayashi1
1Department of Rehabilitation, Kobe City Nishi-Kobe Medical Center, 5-7-1, Kojidai, Nishi-ku, Kobe-shi, Hyogo-ken, 651-2273, Japan.
Clinical nutrition ESPEN
|January 11, 2026
概括
住院时的全身炎症会使肺结核患者的老年人吞功能恶化. 这种炎症是医院住院期间发展食障碍的关键风险因素,增加了其患病率.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 结核病 (TB) 是一个全球性的健康问题,特别影响老年人.
- 吞功能下降 (消化不良) 和其与老年结核病患者全身炎症的联系尚不清楚.
- 在住院期间评估炎症对吞的影响对于患者的治疗结果至关重要.
研究的目的:
- 调查肺结核老年患者入院时系统性炎症和吞功能下降之间的关联.
- 为了确定系统性炎症是否是住院期间发育食障碍的独立风险因素.
主要方法:
- 对119名肺结核患者 (≥65岁) 的回顾性观察研究.
- 使用修改的格拉斯哥预后分数 (mGPS) 评估系统性炎症.
- 在住院期间,功能性口服摄入量表 (FOIS) 的变化测量了吞功能的下降.
主要成果:
- 26.1%的患者在住院期间出现吞能力下降的情况.
- 在入院时,较高的mGPS分数与吞能力下降有显著的关联.
- 在住院期间,食障碍的患病率从12.6%增加到19.3%.
结论:
- 住院时的全身炎症是肺结核患者老年人吞能力下降的重要危险因素.
- 早期评估系统性炎症可能有助于识别患有失消症风险的患者.
- 针对炎症的干预措施可能会减轻住院结核病患者的吞问题.
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