在1型糖尿病儿科人群中非HLA风险变异:临床和自身免疫特征

Miriam Díez Blanco1, Clara Pérez Barrios1, María Encarnación Donoso Navarro1

  • 1Servicio de Bioquímica Clínica - Análisis Clínicos, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.

Anales de pediatria
|January 11, 2026
PubMed
概括

PTPN22,CD226和INS基因的遗传变异在1型糖尿病 (T1D) 的儿童中更为常见. 这些非HLA变异可能提供治疗点,并有助于识别高风险患者以优化后续治疗.

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