单细胞转录组学揭示了垂体神经内分泌瘤中免疫表型的景观

Zhe Zhang1,2, Hong Su3, Jie Yin1,4

  • 1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.

Chinese medical journal
|January 11, 2026
PubMed
概括

下垂体瘤 (PitNETs) 显示出不同的免疫细胞模式. 皮特1系富含调节性T细胞 (Tregs) 和纤维细胞,在Tregs和巨细胞之间发现了一条新发现的CTLA4-CD86通路,影响瘤微环境.

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