相关实验视频

Updated: Jan 13, 2026

2D and 3D Human Induced Pluripotent Stem Cell-Based Models to Dissect Primary Cilium Involvement during Neocortical Development
14:19

2D and 3D Human Induced Pluripotent Stem Cell-Based Models to Dissect Primary Cilium Involvement during Neocortical Development

Published on: March 25, 2022

4.3K

使用iPSCs衍生的神经模型解开人类神经发育的基础上的形态和功能成熟机制

Yue Tian1,2, Yi-Chun Ou1, Zi-Xian Zhang1

  • 1Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center and Neuroscience Research Institute, Peking University, Beijing, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 12, 2026
PubMed
概括

这项研究引入了由干细胞制成的快速人类神经元模型,揭示了L型通道和ECEL1对早期大脑发育和神经元成熟至关重要.

关键词:
卡尔莫杜林3 (CALM3) 是一种末端蛋白转化类似酶1 (ECEL1) 进行转化由hiPSCs衍生的神经元.人类诱导的多能干细胞 (hiPSCs)人类的神经发育电压调节通道的通道电压关闭的离子通道

更多相关视频

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs10:47

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

10.5K
Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays09:20

Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays

Published on: January 8, 2017

27.8K

相关概念视频

EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.3K