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Updated: Jan 13, 2026

Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach
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Published on: February 21, 2019

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可卡因诱导的BRD4互动原子的变化识别了氨酸激酶1埃普西隆作为治疗点

Afshin Seyednejad1,2,3, Tyler J Sacko1,2,3, Christopher J Babigian1

  • 1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.

Journal of neurochemistry
|January 12, 2026
PubMed
概括

研究人员在暴露于可卡因后,在大脑中发现了与BRD4相互作用的新型蛋白质. 抑制氨酸激酶1epsilon (CK1ε) 降低了寻找可卡因的行为,这表明CK1ε是物质使用障碍的潜在治疗标.

关键词:
这就是BRD4D.凯赛因激酶1epsilon 是一种可卡因使用障碍是可卡因使用障碍.质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量它的核心是accumbens的核心.蛋白质蛋白质相互作用

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