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Updated: Jan 13, 2026

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链接组合素H1.5有助于中心分子完整性

Ankita Saha1,2, Minh Bui1, Daniël P Melters1

  • 1National Cancer Institute, Centre for Cancer Research, Laboratory Receptor Biology and Gene Expression, Bethesda, MD 20892, United States.

Nucleic acids research
|January 12, 2026
PubMed
概括

特定的基因素H1变体,如H1.5,与中心色素和CENP-A相互作用. 耗尽H1.5会扰乱中间体转录,CENP-A加载,并导致线粒体缺陷,揭示了线粒体完整性中的作用.

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