低矿物质化第二次初级牙的病因学:系统性审查
Atika Bouabid1,2,3, Rihab Mabrouk1,2,3, Selsebil Laajimi1,2,3
1Faculty of Dental Medicine of Monastir, University of Monastir, Monastir, Tunisia.
概括
低矿化二次初级 (HSPM) 与产前因素 (如母亲吸烟和疾病) 以及产后因素 (如儿童疾病) 有关. HSPM的病因是多因素的,需要进一步研究.
科学领域:
- 儿科牙科 儿科牙科
- 牙科公共卫生 牙科公共卫生
- 发展生物学 发展生物学
背景情况:
- 低矿化二次初级牙 (HSPM) 是影响初级牙的牙缺陷.
- 目前尚不完全了解HSPM的病因,因此需要对当前证据进行审查.
- 本次审查的重点是确定HSPM的潜在病因因素.
研究的目的:
- 综合当前关于低矿化第二大 (HSPM) 的潜在病因因素的证据.
- 评估HSPM病因学现有研究的强度和局限性.
主要方法:
- 按照PRISMA 2020指南进行系统审查.
- 在五个科学数据库进行了全面的搜索.
- 使用纽卡斯尔-太华尺度进行质量和偏见评估.
主要成果:
- 九篇文章符合纳入标准,表明证据基础有限.
- 产前因素,包括表观遗传标记,孕产妇吸烟和孕产妇疾病,显示出与HSPM的最强相关性.
- 产前因素 (早产,分娩并发症) 和产后因素 (重复的儿童疾病) 也存在联系,但证据不那么强大.
结论:
- HSPM可能是多因素的,受产前,产周和产后暴露的影响.
- 目前的证据水平中等,受研究规模,质量和设计的限制.
- 未来需要使用标准化标准进行大规模前性研究,以确定因果关系并加强结论.
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