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声学引起的短延迟消极反应和前道功能在患有扩大前道水道的患者中

Rui-Rui Guan^1,2, Xing-Rong Li², Ying Zhu²

¹Department of Otolaryngology-Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

|January 12, 2026

概括

声学引起的短延迟负响应 (ASNR) 在大前庭水道综合征 (LVAS) 耳朵中更常见,表明前庭功能更好. 在LVAS患者的耳植入后,ASNR的存在预测了保存的前庭结局.

科学领域:

神经科学是一个神经科学.
听力学听力学是指听力学.
耳鼻喉科耳鼻喉科耳鼻喉科

背景情况:

大前庭水道综合征 (LVAS) 是一种先天性内耳形,通常与听力损失和前庭功能障碍有关.
静脉功能评估对于管理LVAS患者至关重要,特别是那些接受耳植入器 (CI) 患者.

研究的目的:

调查声学唤起的短延迟负响应 (ASNR) 与在耳植入 (CI) 之前和之后的LVAS患者的前庭功能之间的关联.
确定ASNR是否可以作为LVAS患者前庭结局的非侵入性预测因子.

主要方法:

64名接受单边CI治疗的患者 (32名LVAS患者,32名对照患者) 的回顾性研究.
评估了ASNR和听觉脑干反应. 在17名LVAS患者的小组中,在CI前和之后使用热量测试和前庭引起的肌原潜力 (VEMPs) 来评估静脉功能.
随访时间平均为4.18年.

主要成果:

与没有内耳形 (12.5%) 的耳朵相比,在LVAS耳朵中 (67.18%) 检测到ASNR的频率明显高.
具有ASNR的LVAS耳朵显示出更好的CI前前庭功能,在热量测试和VEMP中异常率较低.
在CI后,LVAS患者经历了异常热量测试结果的显著增加. 然而,保存的ASNR与正常的宫VEMP (cVEMP) 反应相关,而缺席的ASNR与更高的异常cVEMP率有关.

结论:

在LVAS患者中存在ASNR与更好的前庭功能保存有关,无论是在CI前还是后.
在LVAS患者中,耳植入并没有显著影响耳骨功能.
在接受CI的LVAS患者中,ASNR是前庭结局的有价值的非侵入性预测因子.

关键词:

声学引起的短延迟负面响应.耳植入式耳道植入器大前置水道综合征是什么前庭唤起了肌源性潜能.前体功能前体功能

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