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Updated: Jan 13, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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止痛反应的遗传决定因素:关注慢性疼痛中的CYP2D6和COMT多态性

Anna Bollinger1,2, Céline K Stäuble1,2,3, Isabelle O Urdieux1

  • 1Biopharmacy, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, Switzerland.

The Clinical journal of pain
|January 12, 2026
PubMed
概括

药物遗传学 (PGx) 测试可以确定慢性疼痛患者的药物基因相互作用 (DGI). 由于疼痛敏感性增加,CYP2D6和COMT的遗传变异与治疗失败 (TF) 有关.

关键词:
在PGx面板测试试验中,临床实践中的临床实践高疼痛敏感度 高疼痛敏感度个性化治疗是个性化的治疗.药物基因组学 药物基因组学

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