在2019年冠状病毒病患者中早期评估心肌损伤,使用基于非对比胸部计算机断层扫描的两阶段深度学习框架
Li Wang1, Zhitao Cheng2, Bingyao Liu1
1Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Quantitative imaging in medicine and surgery
|January 12, 2026
概括
深度学习模型现在可以使用非对比性胸部CT扫描在COVID-19患者中预测心肌损伤 (MI). 这项技术为早期MI查和风险分层提供了一个方便的,一站式解决方案.
科学领域:
- 放射学 放射学是一门学科.
- 人工智能的人工智能
- 心脏病学 心脏病学
背景情况:
- 风险分层对于预测2019年冠状病毒病 (COVID-19) 预后至关重要,特别是在心肌损伤 (MI) 方面.
- 无对比胸部计算机断层扫描 (CT) 已被确立用于肺损伤诊断,但其用于同时评估MI的实用性尚不确定.
- 早期MI查和资源分配对于管理COVID-19患者至关重要.
研究的目的:
- 开发和评估一个深度学习 (DL) 框架,用于对COVID-19患者的一步预测MI.
- 评估使用非对比胸部CT用于早期MI查的可行性.
- 为了能够有效地识别高风险患者进行进一步的诊断评估.
主要方法:
- 分析了453名COVID-19患者 (230名心脏病患者,223名没有心脏病患者) 的回顾性队列.
- 采用了两阶段的DL框架:ResNet-101用于左心室 (LV) 细分,DenseNet-121用于MI分类.
- 该框架在413名患者中接受了培训,并通过交叉验证在40名患者中进行了验证.
主要成果:
- 该DL框架在LV细分中实现了高精度 (IoU: 0.8041,ACC: 0.9949,Dice: 0.8672).
- 该框架准确地预测了MI状态,AUC为0.8618 (95%CI:0.8049-0.9187).
- 关键的分类指标包括ACC:0.7763,SEN:0.8750,SPE:0.6071和F1得分:0.8317.
结论:
- 深度学习模型可以有效地从COVID-19患者的非对比胸部CT图像中确定MI状态.
- 这种方法提供了一个方便的,一站式解决方案,用于早期查MI.
- DL框架促进了及时的风险分层和对COVID-19护理的资源优化.
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