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Updated: Jan 13, 2026

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黑猩猩和人类肝细胞癌基因组的不同进化

Lin Kang1,2,3, Katarzyna Michalak1, Robin Varghese2,4

  • 1Division of Biomedical Affairs and Research, Edward Via College of Osteopathic Medicine, Monroe, LA 71203, USA.

Evolution, medicine, and public health
|January 12, 2026
PubMed
概括

与人类HCC相比,黑猩猩肝癌 (HCC) 基因组显示出更高的突变率和频繁的TSC2基因改变. 这项比较基因组学研究揭示了特定物种的癌症途径和保存的驱动因素,为癌症进化和潜在的治疗点提供了洞察力.

关键词:
癌症的演化 癌症的演化癌症基因组学比较研究灵长类动物基因组学身体突变是体质突变.

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