在初级斯乔格伦综合征的病例中,神秘的肺结节
Bodhibrata Banerjee1, Niladri Bhowmick1, Charanpreet Singh2
1Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012 India.
概括
患有肺结节的Sjogren综合征患者可能患有MALT淋巴瘤. 在这种情况下,早期诊断和化疗治疗导致了良好的反应.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
背景情况:
- 肖格伦综合征是一种自身免疫性疾病,通常会影响唾液和眼腺.
- 斯约格伦综合征的肺部参与可以以各种方式表现出来,包括间歇性肺部疾病和结节.
- 马尔特淋巴瘤是一种非霍奇金淋巴瘤,可以发生在各种器官,包括肺部.
研究的目的:
- 在Sjogren综合征患者中报告MALT淋巴瘤病例.
- 强调考虑Sjogren肺结节患者的MALT淋巴瘤的重要性.
- 讨论这种情况的诊断和治疗方法.
主要方法:
- 一个36岁患有Sjogren综合征的女性的案例介绍.
- 诊断工作包括CT扫描和FDG-PET.
- 肺部活检的组织病理学检查.
- 用化疗进行治疗 (里图西马布,环胺,多克索鲁比辛,文克里斯,普雷迪尼索隆).
主要成果:
- 患者出现了渐进的呼吸不全和干咳.
- CT扫描显示了多个结节性空心肺病变,在FDG-PET上是高代谢的.
- 活检证实了MALT的额外节点边缘区域B细胞淋巴瘤.
- 患者对化疗有良好的临床和放射性反应.
结论:
- 在出现多个肺结节的Sjogren综合征患者中,应该怀疑MALT淋巴瘤.
- 及时诊断和适当的化疗可以带来有利的结果.
- 这一案例强调了Sjogren综合征的腺外表现及其与淋巴细胞恶性瘤的关联.
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