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后COVID-19患者的认知障碍:一个前性的神经心理评估研究研究

Charan Sankar Sankaranarayanan¹, Koduvayur Roopa Lakshmi², Mannan Senthilnathan³

¹Department of Neurology and Stroke Medicine, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.

Journal of pharmacy & bioallied sciences

|January 12, 2026

概括

后COVID-19认知障碍,或"大脑雾",是常见的,影响注意力和记忆力. 神经心理测试显示,与对照组相比,COVID后患者的显著缺陷,突出了结构化认知护理的需要.

科学领域:

神经科学是一个神经科学.
传染性疾病传染性疾病
心理学心理学心理学

背景情况:

认知障碍,通常被称为"脑雾",越来越多地被认为是COVID-19恢复后的常见并发症.
对这些认知缺陷的神经心理评估的系统数据有限.

研究的目的:

系统地评估COVID-19后经历认知投诉的患者的认知功能.
将COVID-19后个体的认知表现与没有COVID-19病史的对照组进行比较.

主要方法:

一项前性观察性研究包括120名COVID-19后患者和60名对照,评估时间为2023年2月至2024年12月.
神经心理测试包括蒙特利尔认知评估 (MoCA),Trail Making测试A和B (TMT-A,TMT-B) 和数字跨度测试.
统计分析包括t测试,奇方测试和后勤回归来确定显著的差异和关联.

主要成果:

66.7%的COVID-19后患者表现出认知障碍 (MoCA分数<26) 与15.0%的对照组 (P<0.001) 相比.
后COVID患者在TMT-A (P < 0.001) 和TMT-B (P < 0.001) 上表现明显较慢,这表明注意力和处理速度的缺陷.
通过数字跨度测试评估的工作记忆在COVID后组中也显著受损 (P < 0.001).
最初感染的严重程度 (住院 vs 非住院) 与认知障碍的几率增加相关 (OR: 2.87; P = 0.015).

结论:

认知缺陷,特别是注意力,处理速度和工作记忆,在从COVID-19中恢复过来的个人中很普遍.
结构化的认知查和康复计划可能对长期管理COVID-19后认知后果至关重要.

关键词:

认知障碍认知障碍是一种认知障碍.数字跨度测试数字跨度测试蒙特利尔认知评估蒙特利尔认知评估步道制作测试试验步道制作测试试验

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